Increased TGF-β Signaling Precedes Aneurysm Formation in SMAD3 Deficient Mice
نویسنده
چکیده
Article history: Received 30 September 2016 Accepted 30 September 2016 Available online 5 October 2016 had been referred to Loeys and Dietz since they clearly exhibited a syndromatic phenotype but did not fit other known aneurysm syndromes. Meanwhile the phenotype has broadened and it has been realized that e.g. a bifid uvula is not an essential feature in diagnosing LDS (Loeys et al., 2005). In 2011, van de Laar and colleagues described a group of patients
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